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Python

Cary,NC

973 Python jobs in Cary,NC

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Sr. Software Engineer, Full Stack (AI and Automation)

Manpower Group

Raleigh, NC 27608

New, Posted 1 day ago
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FSP Associate Manager, Safety Data and Systems - Pharmacovigilance

Thermo Fisher Scientific

Cary, NC

Onsite

  • At least Bachelors' degree (or country equivalent) in computer science, data science, computational linguistics, applied statistics/biostatistics, life sciences / Information technology or other relevant field required.
  • Python, ML/NLP frameworks, model deployment/monitoring, MLOps tooling, ideally exposure to LLMs on unstructured clinical/safety text.
  • Working understanding of safety database data models (Argus/ArisG) and E2B(R3) structure.
  • Relevant experience in IT / Safety / Clinical Research / Pharmacovigilance overall with at least 3 years of proven experience with safety database systems (e.g. ARGUS or ArisG) including workflow management
  • Equivalent and adequate combination of education and experience or proven practical expertise in all of the required skills
  • Proficiency in Python for ML development, including scikit-learn, pandas, NumPy; experience with at least one deep learning framework (PyTorch or TensorFlow).
  • Natural language processing for extraction of adverse events, drugs, and outcomes from unstructured text - case narratives, medical literature, call transcripts, and spontaneous reports.
  • Named Entity Recognition (NER), relation extraction, and text classification
  • Experience with transformer-based / large language models (BERT-family, clinical/biomedical models such as BioBERT or PubMedBERT, and modern LLMs) for narrative generation, summarization, and information extraction.
  • MedDRA and WHODrug auto-coding using ML/NLP; prompt engineering and retrieval-augmented generation (RAG) a plus.
  • Supervised and unsupervised methods for classification, clustering, and anomaly detection.
  • Feature engineering and model evaluation (precision/recall trade-offs, ROC/AUC, calibration) with an understanding of why recall and sensitivity are weighted heavily in a safety context.
  • Model lifecycle management: versioning, monitoring, drift detection, retraining pipelines using standard MLOps tooling (e.g. MLflow, Azure ML, Databricks) in line with client DT/BIS standards
  • Model explainability / interpretability (SHAP, LIME) - essential where decisions must be defensible to health authorities.
  • Understanding of GxP / GAMP 5 validation as applied to AI/ML systems, model governance, and emerging regulatory expectations (EMA reflection paper on AI, FDA guidance) — rare and worth flagging as preferred.
  • Proficiency in Safety Database systems (e.g. Argus) and knowledge of other technical systems applicable to Safety /Pharmacovigilance (e.g. E2B gateway, safety signal detection tools and systems) is a plus.
  • Proficiency in electronic systems commonly used for Safety / PV, like for data visualization and analysis, dashboards
  • Solid understanding of the quality management processes, metrics and KPIs
  • Good knowledge of relevant pharmacovigilance regulatory requirements and guidance documents (including Europe, US, Japan)
  • Proficient in the Microsoft 365 stack (Excel, Word, PowerPoint, Teams, SharePoint, OneDrive) and in modern collaboration and documentation tooling
  • Advanced Excel required; working proficiency in SQL required for querying safety and operational datasets
  • Fluent communication in written and spoken English required
  • Ability to work independently with minimal oversight and prioritize effectively
  • Ability to complete multiple complex deliverables within tight timelines
  • Ability to function effectively in a team environment
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Senior Psychometrician

MetaMetrics

Durham, NC 27713

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Software Developer

Kimley-Horn

Raleigh, NC 27608

Flexible Schedule
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Senior Full Stack Engineer

Datavant

Raleigh, NC 27608

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Product Engineer - Software Systems

John Deere

Fuquay Varina, NC 27526

Flexible Schedule
New, Posted 15 hours ago
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Training Specialist & Technical Writer - (Data Center Cooling Solutions)

nVent

Raleigh, NC 27610

RemoteEducation AssistanceHealth InsurancePaid Time OffRetirement Benefit

  • Bachelor's degree in a related field or equivalent work experience.
  • Validated experience providing technical product training and technical writing, preferably in a customer-facing role in the data center space.
  • The ability to digest complex technical concepts from manuals or other materials and translate them into learner-friendly materials.
  • Excellent communication, presentation, and problem-solving skills.
  • Experience working with an LMS or remote training platforms.
  • Ability to work independently and balance multiple training sessions simultaneously.
  • Willingness to travel 25-50% of the time to customer locations as needed.
  • A valid driver's license.
  • Ability to work 100% remotely from a home office anywhere in the US, ideally in CT or ET time zones.
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Mainframe VTAM Systems Programmer/Engineer - Remote

truist

Raleigh, NC 27608

Remote
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Director, Operations SME - Data Centers & Critical Env

Cushman & Wakefield

Raleigh, NC 27608

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IT Professional

US Navy

Raleigh, NC 27610

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