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Systems Architect

Cary,NC

1287 Systems Architect jobs in Cary,NC

New, Posted 12 hours ago
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BCG Platinion | Senior AI Tech Architect

Boston Consulting Group

Durham, NC 27713

~ 28 min OnsiteHealth InsurancePaid Time OffRetirement Benefit

  • Bachelor's degree in information technology, business administration, computer science, information systems, or system controls & engineering or a related field (Master's degree is a plus).
  • 4+ years of technology consulting or software engineering experience with more than 1 year in IT or Business architecture discipline.
  • Gen AI tool fluency (e.g., proven usage of GenAI such as ChatGPT, Claude) and validation of response.
  • Willingness to travel to work with clients and BCG teams. At times, this role involves significant travel to client sites. The amount of travel will depend on client needs and nature of projects.
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New, Posted 16 hours ago
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15Y AH-64D Armament/Electrical/Avionics Systems Repairer

National Guard

Morrisville, NC 27560

~ 17 min OnsiteEducation AssistanceHealth InsuranceRetirement Benefit

  • Military enlistment in the Army National Guard
  • Must be at least a junior in high school, or have a high school diploma or a GED certificate
  • Must be between the ages of 17 and 35
  • Must be able to pass a physical exam and meet legal and moral standards
  • Must meet citizenship requirements (see NATIONALGUARD.com for details)
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Carpentry Install Assistant

Closets by Design Raleigh

Raleigh, NC 27604

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Director - Energy and Physical Plant

Wake County Public School System

Raleigh, NC 27610

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Quality Control Specialist

Cubic Corporation

Durham, NC 27713

~ 28 min Onsite

  • 2 year associates degree required
  • Minimum of 2 years' experience in production.
  • Proficiency in use of Microsoft Office Word, Excel and PowerPoint required.
  • Must possess strong oral and written communication skills and the ability to effectively interface with employees at all levels.
  • Must be objective and self-motivated, requiring minimal supervision.
  • Must have ability to prioritize, progress multiple projects in parallel, and work under deadlines.
  • Strong analytical and problem-solving skills are essential.
  • Must have a positive people-oriented attitude. Able to work in a team environment and approach all challenges openly.
  • Ability to obtain a DOD Security Clearance
  • Cubic Pay Range: $26.00 - $29.00 + benefits.
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Director of Engineering & E-House Business Unit

SMT

Raleigh, NC 27617

$170,000-$220,000/yr
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Diesel Technician

Dollar General Fleet

Wake Forest, NC 27587

$22.95-$32/hr
New, Posted 1 day ago
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Plumber- Duke Raleigh

Duke Health

Raleigh, NC 27610

New, Posted 12 hours ago
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FSP Associate Manager, Safety Data and Systems - Pharmacovigilance

Thermo Fisher Scientific

Cary, NC

Onsite

  • At least Bachelors' degree (or country equivalent) in computer science, data science, computational linguistics, applied statistics/biostatistics, life sciences / Information technology or other relevant field required.
  • Python, ML/NLP frameworks, model deployment/monitoring, MLOps tooling, ideally exposure to LLMs on unstructured clinical/safety text.
  • Working understanding of safety database data models (Argus/ArisG) and E2B(R3) structure.
  • Relevant experience in IT / Safety / Clinical Research / Pharmacovigilance overall with at least 3 years of proven experience with safety database systems (e.g. ARGUS or ArisG) including workflow management
  • Equivalent and adequate combination of education and experience or proven practical expertise in all of the required skills
  • Proficiency in Python for ML development, including scikit-learn, pandas, NumPy; experience with at least one deep learning framework (PyTorch or TensorFlow).
  • Natural language processing for extraction of adverse events, drugs, and outcomes from unstructured text - case narratives, medical literature, call transcripts, and spontaneous reports.
  • Named Entity Recognition (NER), relation extraction, and text classification
  • Experience with transformer-based / large language models (BERT-family, clinical/biomedical models such as BioBERT or PubMedBERT, and modern LLMs) for narrative generation, summarization, and information extraction.
  • MedDRA and WHODrug auto-coding using ML/NLP; prompt engineering and retrieval-augmented generation (RAG) a plus.
  • Supervised and unsupervised methods for classification, clustering, and anomaly detection.
  • Feature engineering and model evaluation (precision/recall trade-offs, ROC/AUC, calibration) with an understanding of why recall and sensitivity are weighted heavily in a safety context.
  • Model lifecycle management: versioning, monitoring, drift detection, retraining pipelines using standard MLOps tooling (e.g. MLflow, Azure ML, Databricks) in line with client DT/BIS standards
  • Model explainability / interpretability (SHAP, LIME) - essential where decisions must be defensible to health authorities.
  • Understanding of GxP / GAMP 5 validation as applied to AI/ML systems, model governance, and emerging regulatory expectations (EMA reflection paper on AI, FDA guidance) — rare and worth flagging as preferred.
  • Proficiency in Safety Database systems (e.g. Argus) and knowledge of other technical systems applicable to Safety /Pharmacovigilance (e.g. E2B gateway, safety signal detection tools and systems) is a plus.
  • Proficiency in electronic systems commonly used for Safety / PV, like for data visualization and analysis, dashboards
  • Solid understanding of the quality management processes, metrics and KPIs
  • Good knowledge of relevant pharmacovigilance regulatory requirements and guidance documents (including Europe, US, Japan)
  • Proficient in the Microsoft 365 stack (Excel, Word, PowerPoint, Teams, SharePoint, OneDrive) and in modern collaboration and documentation tooling
  • Advanced Excel required; working proficiency in SQL required for querying safety and operational datasets
  • Fluent communication in written and spoken English required
  • Ability to work independently with minimal oversight and prioritize effectively
  • Ability to complete multiple complex deliverables within tight timelines
  • Ability to function effectively in a team environment
SmartExplore AI is experimental.
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Power Distribution and Make Ready Designer (Remote)

Sigma Technologies

Raleigh, NC 27601

Remote
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