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System Architect

Durham,NC

561 System Architect jobs in Durham,NC

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Plant Science Technician - Mon-Fri, $21/hr Starting
$21/hr
Onsite
New, Posted 4 hours ago
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BCG Platinion | Lead AI Tech Architect

Boston Consulting Group

Durham, NC 27713

OnsiteHealth InsurancePaid Time OffRetirement Benefit

  • Bachelor's degree in information technology, business administration, computer science, information systems, or system controls & engineering or a related field (Master's degree is a plus)
  • 6+ years of technology consulting or software engineering experience with more than 3+ years in architecture discipline
  • Gen AI tool fluency (e.g., proven usage of GenAI such as ChatGPT, Claude) and validation of response
  • Willingness to travel to work with clients and BCG teams. At times, this role involves significant travel to client sites. The amount of travel will depend on client needs and nature of projects.
  • Ability to explain complex technology topics to senior executives
  • Extensive technical expertise and knowledge along multiple of the following topics: Cloud technologies, architectures, designing cloud workloads and optimizing cloud footprint (i.e., FinOps); Integration methodologies, design patterns and associated tooling (API and Microservices architecture); Structured and unstructured databases and usage patterns; Data platform architecture and associated patterns (e.g. Data Lake, Data Warehouse, Lakehouse, etc.); Data analytics, AI and GenAI architecture; Application modernization, programming paradigms and approaches (e.g. object-oriented); Mainframe architecture; Process automation approaches and tooling (e.g. DevOps, AIOps); An agile mindset that moves past blockers and a vision to iteratively migrate to the modern set of architecture capabilities with a lens of business benefits/value
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Information Systems Technician

U.S. Navy

Hillsborough, NC 27278

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Senior Administrator- Security and Life Safety Manager

Wake County Public School System

Raleigh, NC 27610

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Director of Engineering & E-House Business Unit

SMT

Raleigh, NC 27617

$170,000-$220,000/yr
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Quality Control Specialist

Cubic Corporation

Durham, NC 27713

Onsite

  • 2 year associates degree required
  • Minimum of 2 years' experience in production.
  • Proficiency in use of Microsoft Office Word, Excel and PowerPoint required.
  • Must possess strong oral and written communication skills and the ability to effectively interface with employees at all levels.
  • Must be objective and self-motivated, requiring minimal supervision.
  • Must have ability to prioritize, progress multiple projects in parallel, and work under deadlines.
  • Strong analytical and problem-solving skills are essential.
  • Must have a positive people-oriented attitude. Able to work in a team environment and approach all challenges openly.
  • Ability to obtain a DOD Security Clearance
  • Cubic Pay Range: $26.00 - $29.00 + benefits.
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Maintenance Technician

Resort Lifestyle Communities

Raleigh, NC 27601

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Paramedic I - Code Team - Duke Life Flight - Durham NC

Duke Health

Durham, NC 27713

Onsite

  • High School Diploma
  • NC Paramedic Certification
  • One year Paramedic experience required in an EMS agency
  • BLS Required at hiring
  • ACLS, and PALS are preferred at hiring, but need to be completed by 6 months of hire
  • Current trauma course preferred: PHTLS, BTLS or ITLS
  • Must Speak English in good, understandable terms
  • Pre-employment Physical Capacity Testing Required
  • Must be able to lift and support the weight up to 75 pounds in handling patients, medical equipment, and supplies
  • Intact sense of sight, hearing, smell, and touch
  • Finger dexterity
  • Bimanual Dexterity: Requiring the use of both hands
  • Work requires walking, standing, sitting, lifting, reaching, stooping, bending, kneelling, crouching/squatting, balancing, and pulling
  • Must be able to respond quickly to changes in patient and/or unit conditions
  • Ability to withstand prolonged standing and walking
  • Ability to use computer and learn new software programs
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Phlebotomist - Phlebotomy Services

UNC Health

Chapel Hill, NC 27516

$18.12-$25.51/hr
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CDL A Company OTR Flatbed Drivers

Timco Logistics Systems, LLC

Raleigh, NC 27610

$2,000/wk
$1,000 bonus
~ 31 min OnsiteHealth InsurancePaid Time OffRetirement Benefit

  • 1 year recent driving experience
  • Moving Violations are on a point system
  • No DUI/DWI's in the last 5 years
  • No Felony convictions in the last 5 years
  • MUST HAVE CHAINING AND TARPING EXPERIENCE
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FSP Associate Manager, Safety Data and Systems - Pharmacovigilance

Thermo Fisher Scientific

Durham, NC

Onsite

  • At least Bachelors' degree (or country equivalent) in computer science, data science, computational linguistics, applied statistics/biostatistics, life sciences / Information technology or other relevant field required.
  • Python, ML/NLP frameworks, model deployment/monitoring, MLOps tooling, ideally exposure to LLMs on unstructured clinical/safety text.
  • Working understanding of safety database data models (Argus/ArisG) and E2B(R3) structure.
  • Relevant experience in IT / Safety / Clinical Research / Pharmacovigilance overall with at least 3 years of proven experience with safety database systems (e.g. ARGUS or ArisG) including workflow management
  • Equivalent and adequate combination of education and experience or proven practical expertise in all of the required skills
  • Proficiency in Python for ML development, including scikit-learn, pandas, NumPy; experience with at least one deep learning framework (PyTorch or TensorFlow).
  • Natural language processing for extraction of adverse events, drugs, and outcomes from unstructured text - case narratives, medical literature, call transcripts, and spontaneous reports.
  • Named Entity Recognition (NER), relation extraction, and text classification
  • Experience with transformer-based / large language models (BERT-family, clinical/biomedical models such as BioBERT or PubMedBERT, and modern LLMs) for narrative generation, summarization, and information extraction.
  • MedDRA and WHODrug auto-coding using ML/NLP; prompt engineering and retrieval-augmented generation (RAG) a plus.
  • Supervised and unsupervised methods for classification, clustering, and anomaly detection.
  • Feature engineering and model evaluation (precision/recall trade-offs, ROC/AUC, calibration) with an understanding of why recall and sensitivity are weighted heavily in a safety context.
  • Model lifecycle management: versioning, monitoring, drift detection, retraining pipelines using standard MLOps tooling (e.g. MLflow, Azure ML, Databricks) in line with client DT/BIS standards
  • Model explainability / interpretability (SHAP, LIME) - essential where decisions must be defensible to health authorities.
  • Understanding of GxP / GAMP 5 validation as applied to AI/ML systems, model governance, and emerging regulatory expectations (EMA reflection paper on AI, FDA guidance) — rare and worth flagging as preferred.
  • Proficiency in Safety Database systems (e.g. Argus) and knowledge of other technical systems applicable to Safety /Pharmacovigilance (e.g. E2B gateway, safety signal detection tools and systems) is a plus.
  • Proficiency in electronic systems commonly used for Safety / PV, like for data visualization and analysis, dashboards
  • Solid understanding of the quality management processes, metrics and KPIs
  • Good knowledge of relevant pharmacovigilance regulatory requirements and guidance documents (including Europe, US, Japan)
  • Proficient in the Microsoft 365 stack (Excel, Word, PowerPoint, Teams, SharePoint, OneDrive) and in modern collaboration and documentation tooling
  • Advanced Excel required; working proficiency in SQL required for querying safety and operational datasets
  • Fluent communication in written and spoken English required
  • Ability to work independently with minimal oversight and prioritize effectively
  • Ability to complete multiple complex deliverables within tight timelines
  • Ability to function effectively in a team environment
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