493 Professional Level Systems Engineer jobs in Frederick,MD

B.S. in Mechanical Engineering required
M.S. preferred
5+ years of relevant experience in mechanical design in life science consumable, medical device, pharma, bioprocess components, or other regulated product development environments
10+ years for Level II
Direct experience designing single-use consumables and fluid control assemblies for cell therapy, gene therapy, bioprocessing, or sterile fluid handling systems
Experience with scaling up and high-volume manufacturing
Experience designing bioprocessing technologies such bioreactors, gas exchange, filtration, centrifugation, cell isolation, purification, process analytics, etc.
Strong understanding of fluid handling and fluid control systems, including tubing-based flow paths, pressure-driven flow, pumping, valving, and manifolds
Experience integrating fluid sensing including bubble detection, pressure & liquid sensing, etc.
Experience with FEA preferred (e.g., COMSOL)
Experience designing for GMP manufacturing environments, including cleanroom-compatible use, contamination control, and sterile closed-system processing
Strong knowledge of materials used in GMP manufacturing systems
Experience designing complex mechanical systems, subsystems, and components
Experience designing fluid interfaces and sealing solutions including rotating fluid connections, dynamic seals, face seals, gaskets, and disposable-to-instrument mating mechanisms
Experience with DFx including manufacturing, assembly, reliability, usability, cost, etc.
Experience with tolerance analysis
Proficient in SolidWorks
SolidWorks PDM preferred
Experience with QbD principles, Design for Six Sigma (DFSS), Critical Parameters Design and Management (CPD&M) or similar
Working knowledge of Minitab for statistical analysis and Design of Experiments (DOE) preferred
Skilled in prototyping
Working knowledge of fabrication and assembly methods such as plastic injection molding, 3D printing, CNC machining, sheet metal forming, semi-automated & automated assembly, adhesives, conversion of films and foils, etc.
Working knowledge of metrology tools
Strong knowledge of Design Control (ISO 13485) and GMP compliance for cell therapy manufacturing environments
Familiar with ISO 9001, ISO 10993, ISO14971 and other relevant international safety and quality standards
Experience writing protocols, executing tests, overseeing outsourced testing, and writing reports
Knowledge of extractables/leachable, sterilization methods, particulate control preferred
Strong interpersonal skills with a track record of cross-functional collaboration, problem solving, and driving technical alignment
Excellent written and verbal communication skills
Travel 10-15% domestically

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Entry-Level Border Patrol Agent – $20,000 Sign-On Bonus

U.S. Customs and Border Protection

Hillsboro, VA 20132

$49,739-$89,518/yr

$20,000 bonus

Bilingual Preferred

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Information Systems Technician

U.S. Navy

Charles Town, WV 25414

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Information Technology Professional (IT Support)

US Navy

Poolesville, MD 20837

New, Posted 17 hours ago

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Principal Systems Engineer

Leidos

Gaithersburg, MD 20879

Hybrid~ 32 minPaid Time OffRetirement Benefit

Located in either Gaithersburg, MD or Egg Harbor Township, NJ
Bachelor's degree in Systems Engineering, Computer Science, Engineering, or a related technical field (or equivalent experience)
12+ years of related experience
10+ years of experience with a Master's degree
Experience in systems engineering, product ownership, or related technical leadership roles
Demonstrated experience leading systems engineering efforts on complex, software-intensive programs
Strong experience working in Agile environments (SAFe)
Proficiency with Agile and requirements management tools (e.g., Jira, Confluence, Cameo, Jama, or similar)
Ability to obtain and maintain a Public Trust
US citizenship is required
Successful completion of any required government background investigations
Experience collaborating with architects, engineering leads, and program leadership

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Assistant Professor _ Chemistry

Carroll Community College

Westminster, MD 21157

$52,698-$68,507/yr

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Power Plant Engineer III

MedStar Health

Gaithersburg, MD 20883

$56.39/hr

~ 32 min Onsite

High School Diploma or GED required
Completion of an approved apprentice training program required
Must have a current D.C. Third Class Operating License required
Current CFC License. required
Familiarity with the latest applicable codes standards and regulations including but not limited to: OSHA NFPA The Joint Commission and Fire and Life Safety practices.

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