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Systems Engineering

Lowgap,NC

234 Systems Engineering jobs in Lowgap,NC

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Manufacturing Engineer

AAR

Lowgap, NC

Onsite

  • Manufacturing or Mechanical Engineering Degree (BS) from a four-year college or university and a minimum of five years related experience; or equivalent combination of education and experience.
  • Experience with mechanical systems and lean manufacturing principles.
  • Familiarity with a diverse range of materials (i.e. aluminum alloys, stainless steel alloys, engineering polymers, composites, etc.).
  • Must have the ability to read and interpret engineering drawings, specifications and technical data.
  • Must be capable of applying statistical analysis techniques such as Design of Experiments, Optimization, Process Reliability, Hypothesis Testing and Regression Analysis.
  • Experience with 3-D Modeling software (Uni-graphics, Solid Works, or Solid Edge) is required.
  • Must have strong analytical and mechanical troubleshooting skills.
  • Read, write, speak and understand the English language.
  • Experience within commercial aircraft seating (assembly) environment.
  • Lean implementation with emphasis on standard work & line balancing.
  • Experience establishing operational objectives and performance metrics.
  • DMAIC problem solving
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Principal Engineer- SPE Aux

Westinghouse Electric Company LLC

Lowgap, NC

$103,200-$129,000/yr
Remote

  • 10+ years of experience in engineering, manufacturing or fabrication
  • Bachelor's degree in engineering mechanical, Welding, or Manufacturing disciplines
  • Experience with fabrication and design of ASME Section VIII pressure vessels and heat exchangers
  • Experience in manufacturing processes including machining (turning, milling), welding, forming, mechanical assembly, NDE and inspection, and testing
  • Working knowledge of Manufacturing and Quality Plans
  • Read drawings and specifications made to ASME standard
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Information Systems Technician

US Navy

Mount Airy, NC 27030

New, Posted 1 day ago
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FSP Associate Manager, Safety Data and Systems - Pharmacovigilance

Thermo Fisher Scientific

Lowgap, NC

Onsite

  • At least Bachelors' degree (or country equivalent) in computer science, data science, computational linguistics, applied statistics/biostatistics, life sciences / Information technology or other relevant field required.
  • Python, ML/NLP frameworks, model deployment/monitoring, MLOps tooling, ideally exposure to LLMs on unstructured clinical/safety text.
  • Working understanding of safety database data models (Argus/ArisG) and E2B(R3) structure.
  • Relevant experience in IT / Safety / Clinical Research / Pharmacovigilance overall with at least 3 years of proven experience with safety database systems (e.g. ARGUS or ArisG) including workflow management
  • Equivalent and adequate combination of education and experience or proven practical expertise in all of the required skills
  • Proficiency in Python for ML development, including scikit-learn, pandas, NumPy; experience with at least one deep learning framework (PyTorch or TensorFlow).
  • Natural language processing for extraction of adverse events, drugs, and outcomes from unstructured text - case narratives, medical literature, call transcripts, and spontaneous reports.
  • Named Entity Recognition (NER), relation extraction, and text classification
  • Experience with transformer-based / large language models (BERT-family, clinical/biomedical models such as BioBERT or PubMedBERT, and modern LLMs) for narrative generation, summarization, and information extraction.
  • MedDRA and WHODrug auto-coding using ML/NLP; prompt engineering and retrieval-augmented generation (RAG) a plus.
  • Supervised and unsupervised methods for classification, clustering, and anomaly detection.
  • Feature engineering and model evaluation (precision/recall trade-offs, ROC/AUC, calibration) with an understanding of why recall and sensitivity are weighted heavily in a safety context.
  • Model lifecycle management: versioning, monitoring, drift detection, retraining pipelines using standard MLOps tooling (e.g. MLflow, Azure ML, Databricks) in line with client DT/BIS standards
  • Model explainability / interpretability (SHAP, LIME) - essential where decisions must be defensible to health authorities.
  • Understanding of GxP / GAMP 5 validation as applied to AI/ML systems, model governance, and emerging regulatory expectations (EMA reflection paper on AI, FDA guidance) — rare and worth flagging as preferred.
  • Proficiency in Safety Database systems (e.g. Argus) and knowledge of other technical systems applicable to Safety /Pharmacovigilance (e.g. E2B gateway, safety signal detection tools and systems) is a plus.
  • Proficiency in electronic systems commonly used for Safety / PV, like for data visualization and analysis, dashboards
  • Solid understanding of the quality management processes, metrics and KPIs
  • Good knowledge of relevant pharmacovigilance regulatory requirements and guidance documents (including Europe, US, Japan)
  • Proficient in the Microsoft 365 stack (Excel, Word, PowerPoint, Teams, SharePoint, OneDrive) and in modern collaboration and documentation tooling
  • Advanced Excel required; working proficiency in SQL required for querying safety and operational datasets
  • Fluent communication in written and spoken English required
  • Ability to work independently with minimal oversight and prioritize effectively
  • Ability to complete multiple complex deliverables within tight timelines
  • Ability to function effectively in a team environment
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Steel Operations General Superintendent - Pre-Engineered Metal Buildings

Northstar Steel

Lowgap, NC

$90,000-$115,000/yr
OnsitePaid Time OffRetirement Benefit

  • OSHA 30
  • Minimum of 7 years of hands-on experience in structural steel or pre-engineered metal building erection.
  • Significant experience leading steel erection crews, superintendents, and field operations across multiple sites.
  • Deep knowledge of PEMB erection procedures, structural framing, panel systems, sequencing, and constructability.
  • Proven capability to analyze erection drawings, structural blue prints, specifications, and project schedules.
  • Demonstrated experience coordinating cranes, heavy rigging operations, and field equipment logistics.
  • Valid OSHA 30 or ability to obtain
  • Valid driver's license with the ability to visit active jobsites regularly.
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25B Information Technology Specialist

US ARMY

Blacksburg, VA 24060

~ 1 hr 32 min OnsiteEducation AssistanceHealth InsurancePaid Time OffRetirement Benefit

  • U.S. Citizen
  • 17 to 34 Years Old
  • High School Diploma or GED
  • 10 weeks of Basic Training
  • 20 weeks of Advanced Individual Training
  • Meet Tattoo Guidelines
  • No Major Law Violations
  • No Medical Concerns
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Production Manager – Fenestration & Exterior Envelope Manufacturing

Balanced Unitized Team

Lowgap, NC

OnsiteHealth InsurancePaid Time OffRetirement Benefit

  • 5+ years of relevant leadership experience in fenestration, exterior-envelope, architectural aluminum, window, curtain-wall, panel, cladding, or closely related manufacturing.
  • Direct experience leading people in a manufacturing or fabrication environment.
  • Strong understanding of aluminum fabrication processes, preferably including cutting, milling, drilling, CNC, assembly, or similar production operations.
  • Demonstrated ability to lead, coach, and hold teams accountable.
  • Experience managing production schedules, workflow, staffing, quality, and operational performance.
  • Strong problem-solving ability with experience identifying and correcting manufacturing or process issues.
  • Ability to communicate effectively across the shop floor, management team, engineering, vendors, and executive leadership.
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Own a Mac Tools Franchise | Strong Credit Profile Required

Mac Tools

Jefferson, NC 28640

~ 56 min OnsiteUrgently HiringFlexible Schedule

  • Strong Credit Profile Required
  • A strong credit profile
  • An initial down payment
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Automotive Mechanics

MAVIS TIRE SUPPLY

Elkin, NC 28621

New, Posted 11 hours ago
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Utility Foreman

Steve Tate and Son Plumbing

Mount Airy, NC 27030

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