- Eau Claire
- Ebensburg
- Ebervale
- Edgemont
- Edinboro
- Edinburg
- Effort
- Eighty Four
- Elco
- Elderton
- Eldred
- Elgin
- Elizabeth
- Elizabethtown
- Elizabethville
- Elkins Park
- Elkland
- Elliottsburg
- Ellsworth
- Ellwood City
- Elm
- Elmhurst
- Elmora
- Elrama
- Elton
- Elverson
- Elysburg
- Emeigh
- Emigsville
- Emlenton
- Emmaus
- Emporium
- Endeavor
- Enola
- Enon Valley
- Entriken
- Ephrata
- Equinunk
- Erie
- Ernest
- Erwinna
- Essington
- Etters
- Evans City
- Everett
- Everson
- Export
- Exton
- Factoryville
- Fairbank
- Fairchance
- Fairfield
- Fairhope
- Fairless Hills
- Fairmount City
- Fairview
- Fairview Village
- Fallentimber
- Falls
- Falls Creek
- Fannettsburg
- Farmington
- Farrell
- Fawn Grove
- Fayette City
- Fayetteville
- Feasterville Trevose
- Felton
- Fenelton
- Ferndale
- Finleyville
- Fisher
- Fishertown
- Fleetville
- Fleetwood
- Fleming
- Flicksville
- Flinton
- Flourtown
- Fogelsville
- Folcroft
- Folsom
- Fombell
- Forbes Road
- Force
- Ford City
- Ford Cliff
- Forest City
- Forest Grove
- Forestville
- Forksville
- Fort Hill
- Fort Littleton
- Fort Loudon
- Fort Washington
- Fountainville
- Foxburg
- Frackville
- Franconia
- Franklin
- Franklintown
- Frederick
- Fredericksburg
- Fredericktown
- Fredonia
- Freeburg
- Freedom
- Freeland
- Freeport
- Frenchville
- Friedens
- Friedensburg
- Friendsville
- Fryburg
- Furlong
- Gaines
- Galeton
- Gallitzin
- Gans
- Gap
- Garards Fort
- Gardenville
- Gardners
- Garland
- Garnet Valley
- Garrett
- Gastonville
- Geigertown
- Genesee
- Georgetown
- Germansville
- Gettysburg
- Gibbon Glade
- Gibson
- Gibsonia
- Gifford
- Gilbert
- Gilberton
- Gilbertsville
- Gillett
- Gipsy
- Girard
- Girardville
- Gladwyne
- Glasgow
- Glassport
- Glen Campbell
- Glen Hope
- Glen Lyon
- Glen Mills