Plasma ctDNA workflows including cfDNA extraction and hybrid capture library preparation such as TSO500 ctDNA or equivalent assays
BS or MS in molecular biology, genetics, genomics, biochemistry, or a related field
Demonstrated experience with clinical sample types, ideally including FFPE tissue and plasma, and the ability to make sound QC decisions under real world sample constraints
5 plus years of hands on NGS laboratory experience with demonstrated ownership of workflows end to end and a track record of troubleshooting and stabilizing production assays
Experience with lab automation or semi automation for extraction and or library preparation using platforms such as KingFisher, Beckman, Hamilton, Tecan, or equivalents
Tumor DNA sequencing including WES or hybrid capture panels, ideally from FFPE
Strong documentation practices and experience operating in GLP, GCP, or CAP aligned environments are strongly preferred
FFPE RNA sequencing or gene expression profiling, including low input and degraded RNA handling
Comfort interpreting run level QC metrics and coordinating effectively with bioinformatics partners for rapid issue triage and clean data delivery
Strong molecular biology fundamentals including nucleic acid extraction, PCR or qPCR-based quantification where applicable, and instrument-based QC using Tape Station or Bioanalyzer, Qubit, Nanodrop, Fragment Analyzer, or similar tools
Strong hands-on experience running Illumina sequencing workflows end to end on platforms such as NextSeq, NovaSeq, or NovaSeq X, including library QC, pooling strategy, loading, run setup, run monitoring, and troubleshooting
Hands-on experience in at least two of the following areas, with willingness to support all three as needed

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